Highly Sensitive Coherent Anti-Stokes Raman Scattering Imaging of Protein Crystals.

نویسندگان

  • Grigory M Arzumanyan
  • Nelya V Doroshkevich
  • Kahramon Z Mamatkulov
  • Sergey N Shashkov
  • Egor V Zinovev
  • Alexey V Vlasov
  • Ekaterina S Round
  • Valentin I Gordeliy
چکیده

Serial crystallography at last generation X-ray synchrotron sources and free electron lasers enabled data collection with micrometer and even submicrometer size crystals, which have resulted in amazing progress in structural biology. However, imaging of small crystals, which although is highly demanded, remains a challenge, especially in the case of membrane protein crystals. Here we describe a new extremely sensitive method of the imaging of protein crystals that is based on coherent anti-Stokes Raman scattering.

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عنوان ژورنال:
  • Journal of the American Chemical Society

دوره   شماره 

صفحات  -

تاریخ انتشار 2016